Introduction of PI

Xiang Li, PhD Faculty of Life and Health Sciences Shenzhen University of Advanced Technology

Molecular mechanism of prion-like proteins in neurodegenerative diseases

Research Area

Molecular mechanism of prion-like proteins in neurodegenerative diseases

Neurodegenerative diseases are a group of conditions that cause the progressive loss of nerve cells in the brain and spinal cord, leading to damage or death of neurons and subsequent loss of cognitive, physical, and behavioral abilities. Caused by various factors, including genetic mutations, environmental toxins, and aging, neurodegenerative diseases include Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). Our overall research goal is to determine how prion-like proteins, such as amyloid beta, TDP-43 and a-Synuclein, are involved in various neurodegenerative diseases, and to enhance drug development based on information of their function and structure